The authors examined the use of a two single, portable incisional negative pressure wound therapy (INPWT) systems for incisional healing and complex incisions that required debridement following surgical revision. A single-centre small evaluation was performed in the UK and, due to its successes, this ongoing evaluation was escalated to three other sites across Asia. Five case studies are presented in this article, comprising three females and two males with a mean age of 50.4 years. All patients’ wounds broke down following surgery — two patients had surgical revisions for pilonidal sinus and hip replacement, while other operations included varicose vein surgery and amputation of a limb for critical ischaemia and removal of an abscess following a trauma injury. This evaluation demonstrated that both systems have the potential to improve patient outcomes following surgery, but where moderate to heavy exudate was present, the canister system, with variable pressure settings, was preferred as it lasted up to 15 days as opposed to the other system, which lasted 3–7 days. Both systems were liked by the patients and all patients were followed up for 6 weeks in outpatient departments. This evaluation led to the understanding of some of the potential reasons for incisional breakdown, and potentially preventing them.